case for Leitz LMBI-T laboratory binocular compound microscope
Date: circa 1953
Inventory Number: 2009-1-0011b
Classification: Microscope
Dimensions:24.5 × 42.8 × 26 cm (9 5/8 × 16 7/8 × 10 1/4 in.)
Accessories: objectives (4); eyepieces (8); oil bottle; dropper bottle; cover slips; case.
DescriptionThis is a Leitz laboratory binocular compound microscope of the LMBI-T design. It has a modern, inclinable stand with a V-shaped cast-iron base. The arm is a curved handle attached to an upright rectangular support that carries the rack and pinion and focusing knobs. The end of the arm carries an inclined binocular tube marked 1.25x. The interpupillary distance is adjustable by means of a calibrated knob. There is a chrome-plated quadruple, revolving nosepiece. The coarse and fine focuses appear to be made of nickel. Coarse focus is by rack and pinion. Fine focus is by micrometer screw.
The square mechanical stage has two verniers. Adjustments in x-y directions are made by a two nickel knobs mounted concentrically on the same axis. The substage illuminating apparatus includes a condenser with a small swing-out lens in addition to the large central lens. There is also a removable iris diaphragm and a swing out glass filter. The condenser is mounted on a vertical frame that can be adjusted up and down by rack and pinion. The base has a plano-concave mirror.
Eyepieces include a pair of Periplan 10x, a 10x B, and a 6x B, all Leitz. The last two are stored in a tall, plastic jar with a screw lid. There is an unsigned 10x wide angle, a 10x, and an unmarked eyepiece. There is also one Bausch & Lomb 10x eyepiece.
Objectives include the following:
C 1/12, oil immersion 100:1, A 1.30
3, 10:1, A 0.25
6L, 45:1, A 0.65
1h, 3.5:1, A 0.10
The canisters are all present and marked.
The fitted case is made of wood, covered in leatherette, and lined with a deep burgundy felt. It has metal corner protectors and three latches. The handle is missing.
Accessories in the case include a bottle of immersion oil (n/D = 1.515, v=49). It is dated "6. 12. 52." There is a glass oil dropper bottle of clear and amber glass. Two boxes of cover slips, partly used, were made in the USA.
Also found in the case are two laboratory prepared slides with stained specimens. One is marked, "DOG / #473 / 6 m," and the other is marked "aortic / essaft [?] / 70% IMO. / H.E F."
Signedon vertical rack, on objectives 1/12 oel, 6L, and 3, and on canisters for the same plus 1h: E. LEITZ / WETZLAR [in achromat trademark]
on vertical rack, and on objectives 1/12, 6L, and 3: Germany
on binocular tube: Ernst Leitz / Wetzlar / Germany
on objective 1h: Ernst Leitz Wetzlar
on Periplan 10x eyepieces: LEITZ WETZLAR GERMANY
on 10x B, 6x B eyepieces: Ernst Leitz Wetzlar
on 10x eyepiece: B&L OPT. CO. U.S.A.
stamped on underside of cover slip boxes: ADAMS [in trademark cross, surrounded by] GOLD SEAL / NON-CORROSIVE
on lid of cover slip boxes: MADE IN U. S. A.
Inscribedserial number on vertical rack: 436865
by fine focus knob: 1 Intervall / 0.001 m/m
on binocular tube: 1,25x
on embossed plastic label tape on microscope arm: DR. FOLKMAN
on embossed plastic label tape on case lid: J. FOLKMAN
Historical AttributesWhen he entered Harvard Medical School in 1953, Judah Folkman purchased this Leitz microscope as a replacement for the Spencer microscope he had used from age thirteen. This microscope was used by Dr. Folkman through the mid-1970s during which time he laid the foundation for novel angiogenesis research which led, over the next forty years, to new therapies for cancer, macular degeneration, and other diseases that involved abnormal blood vessel formation. The concept of angiogenesis provided "an organizing principle of biology, essential for the growth of any mass from a cancerous tumour to an atherosclerotic plaque." [Nature 451 (14 February 2008): 781.]
(For more details about Judah Folkman's research with this instrument, please see the documents and references attached to this object record and the biography of Dr. Folkman.)
Primary SourcesWilliam D. Figg and Judah Folkman, eds., Angiogenesis: An Integrative Approach from Science to Medicine (New York: Springer, 2008).
ProvenanceJudah Folkman, Harvard Medical School, Boston, Mass., 1953-2008; gift to CHSI by Paula Folkman, Dr. Folkman's widow, Brookline, Mass., 2009.
Related WorksRobert Cooke, Dr. Folkman's War: Angiogenesis and the Struggle to Defeat Cancer, forward by C. Everett Koop (Random House, 2001).